O24 - Mite allergy prevention study
نویسندگان
چکیده
Background Infants with family history of atopy are considered at high risk for developing allergic disease. Environmental exposures are modifiable risk factors with a potential for intervention to prevent allergy. Children who develop house dust mite (HDM) sensitisation by pre-school age are at higher risk of developing asthma. Prevention of HDM sensitisation in early childhood by immune modulation may consequently prevent development of asthma. We sought to achieve this by inducing tolerance to HDM through high dose allergen exposure.
منابع مشابه
Mite and pet allergen levels in homes of children born to allergic and nonallergic parents: the PIAMA study.
The Prevention and Incidence of Asthma and Mite Allergy (PIAMA) study is a birth cohort study that investigates the influence of allergen exposure on the development of allergy and asthma in the first several years of life. The objectives of this study were to investigate the relationship between a family history of allergy and/or asthma and exposure of newborn children to mite and pet allergen...
متن کاملMites and house dust mite allergy in bronchial asthma in Northern Zambia.
Of 100 asthmatic patients prick tested for allergy to Dermatophagoides pteronyssinus, 88% were positive compared with only 14% of controls. A significantly greater proportion of dust samples from the houses of the asthmatics contained Dermatophagoides mites. The house-dust mite D. pteronyssinus, constituted 90% of the mites identified, other pyroglyphid mites, Cheyletus and Glycophagus making u...
متن کاملInternational consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem
Since mite allergens are the most relevant inducers of allergic diseases worldwide, resulting in significant morbidity and increased burden on health services, the International Collaboration in Asthma, Allergy and Immunology (iCAALL), formed by the American Academy of Allergy, Asthma and Immunology (AAAAI), the American College of Allergy, Asthma and Immunology (ACAAI), the European Academy of...
متن کاملRandomized trial to prevent sensitization to mite allergens in toddlers and preschoolers by allergen reduction and education: one-year results.
OBJECTIVE To evaluate the effectiveness of prevention measures against dust mite sensitization. DESIGN European (England, Germany, Greece, Lithuania) multicenter prospective single-blind randomized control trial with a follow-up of 12 months. PARTICIPANTS Toddlers and preschoolers, with at least 1 parent with atopic symptoms and sensitization, who initially were not sensitized to mite aller...
متن کاملAllergen exposure in infancy and the development of sensitization, wheeze, and asthma at 4 years.
BACKGROUND The relationship between mite and pet allergen exposure in infancy and the subsequent development of sensitization and asthma is complex. OBJECTIVE We prospectively investigated the effect of allergen exposure at 3 months of age on the development of sensitization, wheeze, and physician-diagnosed asthma in the first 4 years of life in a birth cohort of children with and without an ...
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